Drug Uses
Tofranil is used for treatment of depression. It is also used in some children to help reduce bedwetting. It may also be used for other conditions as determined by your doctor.

How Taken
Use Tofranil as directed by your doctor. Take Tofranil with or without a meal. Taking Tofranil at bedtime may help reduce side effects (eg, daytime drowsiness). Discuss this possibility with your doctor. It may take 1 to 3 weeks before you notice the effect of Tofranil. Continue to use Tofranil even if you feel well.

Warnings/Precautions
Before taking Tofranil, tell your doctor or pharmacist if you have any medical conditions, especially if you have allergies to medicines, if you are allergic to any ingredient in Tofranil, if you have a history of suicidal thoughts or behavior, bipolar disorder, or any other mental disorders, you are undergoing electroshock therapy, or you are scheduled to have any surgery, if you are taking thyroid medicine or you have a history of overactive thyroid, glaucoma, heart problems, kidney or liver problems, diabetes, seizures, the blood disease porphyria, or difficulty urinating if you consume alcohol–containing beverages daily or you have a history of alcohol abuse, if you are pregnant, planning to become pregnant or are breast–feeding. It is unknown if Tofranil can cause harm to the fetus. If you become pregnant while taking Tofranil, discuss with your doctor the benefits and risks of using Tofranil during pregnancy. It is unknown if Tofranil is excreted in breast milk. Do not breast–feed while taking Tofranil. Some medicines may interact with Tofranil. Therefore tell your doctor of all prescription or nonprescription medicine, herbal preparation, or dietary supplement that you are taking. Do not take Tofranil if you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days, or if you are taking astemizole, dofetilide, droperidol, terfenadine, or cisapride or if you are recovering from a recent heart attack. Alcohol, hot weather, exercise, and fever can increase dizziness. To prevent dizziness or fainting, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness. Antidepressants can increase suicidal thoughts and behaviors in some children and teenagers. This risk may be higher in individuals with bipolar illness (also called manic–depressive illness), a family history of bipolar illness, or a history of attempting suicide. You should pay close attention to changes in moods or actions, especially if changes occur suddenly. Contact your doctor right away if any of the following effects occur or worsen- depression, anxiety, restlessness or irritability, panic attacks, thoughts or attempts of suicide, or other unusual changes in behavior or mood. Tofranil may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Tofranil. Use a sunscreen or protective clothing if you must be outside for a prolonged period. Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Tofranil. Elderly patients may be more sensitive to the effects of Tofranil and might require a lower dose. Do not use Tofranil in children younger than 6 years of age. Safety and effectiveness in this age group have not been established.

Missed Dose
If you miss a dose take it as soon as you remember. However if it is almost time for the next dose, skip the Missed Dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Possible Side Effects
Some of the Possible Side Effects are- Dizziness, drowsiness, dry mouth, excitement, headache, impotence, nausea, nightmares, pupil dilation, and sensitivity to sunlight, sweating, tiredness, upset stomach, vomiting, weakness, weight loss or gain. Contact your doctor if any of these or other side effects occur. If you experience any of the following serious side effects, you should seek medical attention immediately- allergic reactions (rash, hives, itching, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue), blurred vision or other vision changes, changes in sex drive, chest pain, confusion, constipation, fainting, fever, frequent or difficult urination, hallucinations, impulsive behaviour or other unusual changes in behaviour, fast, slow, or irregular heartbeat, jaw, neck, or muscle spasms, mental or mood changes (eg, increased anxiety, mood swings, agitation, irritability, nervousness, restlessness), panic attacks, ringing in the ears, seizures, severe dizziness or drowsiness, sore throat, stomach pain, suicidal thinking or behaviour, swelling of the testicles, tremor, trouble sleeping, trouble walking or keeping your balance, twitching of the face or tongue, uncontrolled movements of arms and legs or stiffness, unusual bleeding or bruising, worsening of depression, yellowing of the skin or eyes.

Storage
Store Tofranil at 68 – 77 °F (68 – 25 °C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tofranil out of the reach of children.

Overdose
If overdose is suspected seek medical attention immediately. Some of the symptoms of Tofranil overdose are- agitation, bluish skin or mucous membranes, breathing problems, chest pain, coma, confusion, dry mouth, enlarged pupils, excess sweating, fainting, fast or irregular heartbeat, flushing, incoordination, involuntary movements, loss of consciousness, restlessness, rigid muscles, seizures, severe drowsiness, shock, stupor, vomiting.

More Information
Tofranil may cause drowsiness, dizziness, or blurred vision. These effects may worsen if Tofranil is taken with alcohol or certain other medications. Use Tofranil with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to this drug. If your symptoms do not improve or if they worsen, contact your doctor. Tofranil should be used only by the patient for whom it has been prescribed. Do not take less or more or take it more often than prescribed by your doctor

Disclaimer
This is only general information, it does not cover all directions, drug integrations or precautions. You should not rely on it for any purpose, it does not contain any specific instructions for a particular patient. We disclaim all responsibility for the accuracy and reliability of this information. We`re not responsible for any damage.